Our biggest ideas come from the tiniest things: photons and atoms, molecules and microorganisms, nanoparticles and nanopores. These are the building blocks we use to create a better future. Our work takes place on a shifting frontier where basic science meets technology, extending the boundaries of what is possible. We use chemistry, biology, physics, mathematics, computational methods, and engineering fundamentals to create solutions for some of the greatest challenges facing humanity, including sustainable energy and chemical production, clean air and water, and advanced health informatics.